Online Table 5:
Net reclassification of 10-year cardiovascular disease risk into low (<7.5%) and high (≥7.5%) risk groups, comparing model A (based on established CVD risk factors) to model B (based on established CVD risk factors plus hypertensive disorders of pregnancy and parity) among women with incident CVD and those without incident CVD
| Model B: Established CVD Risk Factors | |||
| Plus Hypertensive Disorders of Pregnancy and Parity | |||
| Categories of Predicted 10-Year Risk | |||
| Model A: Established CVD Risk Factors | Low Risk: | High Risk: | Total |
| Categories of Predicted 10-Year Risk | <7.5% | ≥7.5% | Reclassified |
| Women with incident CVD (n=685) | |||
| Low Risk: <7.5% | |||
| N | 682 | 2 | 2 |
| % Reclassified | --- | 0.3 | 0.3 |
| High Risk: ≥7.5% | |||
| N | 0 | 1 | --- |
| % Reclassified | --- | --- | --- |
| Women without incident CVD (n=105,545) | |||
| Low Risk: <7.5% | |||
| N | 105,500 | 13 | 13 |
| % Reclassified | --- | 0.01 | 0.01 |
| High Risk: ≥7.5% | |||
| N | 5 | 27 | 5 |
| % Reclassified | 15.6 | --- | 15.6 |
Abbreviation: CVD: cardiovascular disease. Established risk factors include age, total cholesterol, high-density lipoprotein cholesterol, systolic blood pressure, anti-hypertensive medication use, current smoking, and diabetes. NRI = 0.003; 95% CI: -0.0001, 0.006; P = 0.14. NRI for events = 0.003; 95% CI: 0.000, 0.006; P = 0.13. NRI for non-events = -0.0001; 95% CI: -0.0002, -0.000001; P = 0.04.