Online Table 6:
Net reclassification of 10-year cardiovascular disease risk into low (<7.5%) and high (≥7.5%) risk groups, comparing model A (based on established CVD risk factors) to model B (based on established CVD risk factors plus hypertensive disorders of pregnancy and parity) among women with incident CVD and those without incident CVD at ages 40–49
| Model B: Established CVD Risk Factors Plus Hypertensive Disorders of Pregnancy and Parity | |||
| Categories of Predicted 10-Year Risk | |||
| Model A: Established CVD Risk Factors | Low Risk: <7.5% | High Risk: ≥7.5% | Total Reclassified |
| Categories of Predicted 10-Year Risk | |||
| Women with incident CVD (n=359) | |||
| Low Risk: <7.5% | |||
| N | 358 | 0 | --- |
| % Reclassified | --- | --- | --- |
| High Risk: ≥7.5% | |||
| N | 0 | 1 | --- |
| % Reclassified | --- | --- | --- |
| Women without incident CVD (n=73,693) | |||
| Low Risk: <7.5% | |||
| N | 73,679 | 5 | 5 |
| % Reclassified | --- | 0.01 | 0.01 |
| High Risk: ≥7.5% | |||
| N | 1 | 8 | 1 |
| % Reclassified | 11.1 | --- | 11.1 |
Abbreviation: CVD: cardiovascular disease. Established risk factors include age, total cholesterol, high-density lipoprotein cholesterol, systolic blood pressure, anti-hypertensive medication use, current smoking, and diabetes. NRI = -0.00005; 95% CI: -.0001, 0.000; P = 0.08. NRI for events = inestimable. NRI for non-events = -0.00005; 95% CI: -0.0001, 0.000; P = 0.08.