Table 2:

Cumulative incidence and hazard ratios for 10-year risk of CVD by hypertensive disorders of pregnancy and parity, overall and stratified by age at start of interval

Crude Model	Cases/Person-Years	10-Year Cumulative Incidence*	HR (95% CI)	P Value
Overall
Nulliparous	129/178,380	72	1.23 (0.98, 1.53)	0.07
Normotensive pregnancy and para 1	104/124,173	84	1.42 (1.12, 1.80)	<0.01
Normotensive pregnancy and para 2	208/352,711	60	1.00 (ref)	—
Normotensive pregnancies and para >3	149/241,544	62	1.05 (0.85, 1.29)	0.68
History of HDP and para 1	18/18,563	98	1.64 (1.01, 2.66)	0.04
History of HDP and para 2	54/45,346	118	2.02 (1.50, 2.72)	<0.001
History of HDP and para >3	23/31,504	74	1.24 (0.80, 1.90)	0.34
Ages 40–49
Nulliparous	67/120,209	55	1.30 (0.95, 1.76)	0.10
Normotensive pregnancy and para 1	58/82,163	72	1.64 (1.19, 2.27)	<0.01
Normotensive pregnancy and para 2	103/239,615	44	1.00 (ref)	—
Normotensive pregnancies and para >3	76/166,698	46	1.06 (0.79, 1.43)	0.70
History of HDP and para 1	11/12,741	89	2.00 (1.08, 3.73)	0.03
History of HDP and para 2	33/31,490	104	2.43 (1.64, 3.60)	<0.001
History of HDP and para >3	11/22,559	49	1.13 (0.61, 2.11)	0.70
Ages 50–59
Nulliparous	62/58,171	106	1.15 (0.84, 1.57)	0.39
Normotensive pregnancy and para 1	46/42,010	108	1.18 (0.83, 1.67)	0.35
Normotensive pregnancy and para 2	105/113,096	92	1.00 (ref)	—
Normotensive pregnancies and para >3	73/74,846	97	1.05 (0.78, 1.42)	0.75
History of HDP and para 1	7/5,822	120	1.29 (0.60, 2.78)	0.51
History of HDP and para 2	21/13,857	150	1.63 (1.02, 2.61)	0.04
History of HDP and para >3	12/8,945	133	1.45 (0.80, 2.63)	0.23

Abbreviations: CVD: cardiovascular disease. CI: confidence intervals. HDP: hypertensive disorder of pregnancy. HR: hazard ratio.

*Cumulative incidences per 10,000 women shown above are Kaplan-Meier estimates, which account for censoring.