Table 1.
Relationship between SHMT2 expression and conventional clinicopathological parameters in human intrahepatic cholangiocarcinoma.
Clinicopathological parameters | n | SHMT2 expression | P ∗ | |
---|---|---|---|---|
Low | High | |||
Gender | 0.959 | |||
Female | 31 | 15 | 16 | |
Male | 69 | 33 | 36 | |
Age (years) | 0.987 | |||
<60 | 52 | 25 | 27 | |
≥60 | 48 | 23 | 25 | |
Tumor size (cm) | 0.935 | |||
≤5 | 40 | 19 | 21 | |
>5 | 60 | 29 | 31 | |
Tumor number | 0.351 | |||
Solitary | 91 | 45 | 46 | |
Multiple | 9 | 3 | 6 | |
Vascular invasion | 0.120 | |||
No | 64 | 27 | 37 | |
Yes | 36 | 21 | 15 | |
Pathological grade | 0.361 | |||
I | 4 | 3 | 1 | |
II | 62 | 27 | 35 | |
III | 34 | 18 | 16 | |
T stage | 0.017∗ | |||
T1 | 42 | 26 | 16 | |
T2 | 47 | 20 | 27 | |
T3–T4 | 11 | 2 | 9 | |
N stage | 0.318 | |||
N0 | 86 | 43 | 43 | |
N1 | 14 | 5 | 9 | |
Metastasis | 0.261 | |||
No | 96 | 45 | 51 | |
Yes | 4 | 3 | 1 | |
TNM stage | 0.041∗ | |||
I | 34 | 22 | 12 | |
II | 42 | 18 | 24 | |
III–IV | 24 | 8 | 16 |