Table 5.

Curated 36 cancer-related TF families.

Family	Full Name	Members (Official Gene Symbols)
AP1	Activator Protein 1	FOS, FOSB, JUN, JUNB, JUND
AP2	Activator Protein 2	TFAP2A, TFAP2B, TFAP2C, TFAP2D, TFAP2E
AR	Androgen Receptor	AR
ATF	Activating Transcription Factor	ATF1 – 7
BCL	B-cell CLL/lymphoma	BCL3, BCL6
BRCA	breast cancer susceptibility protein	BRCA1 – 3
CEBP	CCAAT/enhancer binding protein	CEBPA, CEBPB, CEBPD, CEBPE, CEBPG
CREB	cAMP responsive element binding protein	CREB1 - 5, CREM
E2F	E2F transcription factor	E2F1 – 7
EGR	early growth response protein	EGR1 – 4
ELK	member of ETS oncogene family	ELK1, ELK3, ELK4
ER	Estrogen Receptor	ESR1, ESR2
ERG	ets-related gene	ERG
ETS	ETS-domain transcription factor	ETS1, ETS2, ETV4, SPI1
FLI1	friend leukemia integration site1	FLI1
GLI	glioma-associated oncogene homolog	GLI1 - 4
HIF	Hypoxia-inducible factor	HIF1A, ARNT, EPAS1, HIF3A
HLF	hepatic leukemia factor	HLF
HOX	homeobox gene	HOXA, HOXB, HOXD series, CHX10, MSX1, MSX2, TLX1, PBX2
LEF	lymphoid enhancing factor	LEF1
MYB	myeloblastosis oncogene	MYB, MYBL1, MYBL2
MYC	myelocytomatosis viral oncogene homolog	MYC
NFI	nuclear factor I; CCAAT-binding transcription factor	NFIA, NFIB, NFIC, NFIX
NFKB	Nuclear factor kappa B, reticuloendotheliosis oncogene	NFKB1, NFKB2, RELA, RELB, REL
OCT	Octamer binding proteins	POU2F1 - 3, POU3F1 - 2, POU5F1
p53	P53 family	TP53, TP73L, TP73
PAX	paired box gene	PAX1 – 9
PPAR	Peroxisome proliferator-activated receptor	PPARA, PPARD, PPARG
PR	Progesterone Receptor	PGR
RAR	retinoic acid receptor	RARA, RARB, RARG
SMAD	Mothers Against Decapentaplegic homolog	SMAD1 - 9
SP	sequence-specific transcription factor	SP1 – 8
STAT	signal transducer and activator of transcription	STAT1 - 6
TAL1	T-cell acute lymphocytic leukemia-1 protein	TAL1
USF	upstream stimulatory factor	USF1, USF2
WT1	Wilms tumor 1 (zinc finger protein)	WT1