(d) Top 10 enriched KEGG pathway of key genes

Pathway Name	Pathway ID	P value	Count
p53 signaling pathway	hsa04115	8.24E-09	7
Cell cycle	hsa04110	1.31E-04	5
Retinol metabolism	hsa00830	1.31E-04	4
AMPK signaling pathway	hsa04152	1.36E-04	5
Drug metabolism - cytochrome P450	hsa00982	1.65E-04	4
Metabolism of xenobiotics by cytochrome P450	hsa00980	2.06E-04	4
Progesterone-mediated oocyte maturation	hsa04914	6.36E-04	4
Oocyte meiosis	hsa04114	1.49E-03	4
Steroid hormone biosynthesis	hsa00140	1.65E-03	3
FoxO signaling pathway	hsa04068	2.04E-03	4