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. 2018 Aug 29;2018:3570830. doi: 10.1155/2018/3570830

Figure 2.

Figure 2

The effect of cinnamaldehyde on the lifespan of Alzheimer's disease (AD) flies overexpressing Aβ 42. (a, b) 16 mM of cinnamaldehyde (CM) had no significant effect on the lifespan of AD flies overexpressing the Aβ42 protein (male control n = 114, male CM n = 113, female control n = 112, and female CM n = 112, P > 0.05). (c, d) 80 mM of cinnamaldehyde significantly increased the lifespan of male AD fly model overexpressing the Aβ42 protein by 5.7% (male control n = 114, male CM n = 115, P < 0.0001) and it had no significant impact on the lifespan of females (female control n = 112, female CM n = 113, P > 0.05). (e, f) 400 mM of cinnamaldehyde was toxic to AD flies overexpressing the Aβ42 protein in both males and females (male control n = 114, male CM n = 113, female control n = 112, and female CM n = 115, P < 0.001).