Table 2.
Effects of Mn exposure and AAH pretreatment on ROS and GSH levels in neurons.
Group | ROS (μmol/g pro) | GSH (μmol/g pro) |
---|---|---|
Control | 179.93 ± 3.61 | 26.85 ± 7.26 |
100 μM MnCl2 | 191.79 ± 13.27 | 20.71 ± 4.11∗ |
200 μM MnCl2 | 254.62 ± 6.85∗∗ | 17.72 ± 4.33∗∗ |
400 μM MnCl2 | 324.48 ± 6.74∗∗ | 15.31 ± 3.08∗∗ |
250 μM AAH + 400 μM MnCl2 | 390.9 ± 12.38∗∗## | 9.82 ± 1.64∗∗# |
1 mM NAC + 400 μM MnCl2 | 205.94 ± 6.09∗∗## | 25.35 ± 5.88# |
Data are mean ± SD; n = 6 each. ∗p < 0.05, ∗∗p < 0.01 denote statistical significance compared with the control group; #p < 0.05, ##p < 0.01 denote statistical significance compared with the MnCl2 alone group.