Table 3.
Effects of Mn exposure and SSZ pretreatment on ROS and GSH levels in astrocytes.
Group | ROS (μmol/g pro) | GSH (μmol/g pro) |
---|---|---|
Control | 191.51 ± 3.36 | 23.49 ± 5.37 |
100 μM MnCl2 | 199.62 ± 6.74 | 20.61 ± 6.72 |
200 μM MnCl2 | 254.69 ± 9.74∗∗ | 17.97 ± 3.12∗ |
400 μM MnCl2 | 296.46 ± 8.19∗∗ | 16.18 ± 3.11∗∗ |
200 μM SSZ + 400 μM MnCl2 | 324.86 ± 4.55∗∗## | 10.16 ± 0.71∗∗# |
1 mM NAC + 400 μM MnCl2 | 218.49 ± 7.04∗∗## | 20.61 ± 5.79# |
Data are mean ± SD; n = 6 each. ∗p < 0.05, ∗∗p < 0.01 denote statistical significance compared with the control group; #p < 0.05, ##p < 0.01 denote statistical significance compared with the MnCl2 alone group.