Table 4.
Effects of Mn exposure and AAH or SSZ pretreatment on ROS and GSH levels in the striatum.
| Group | ROS (μmol/g pro) | GSH (μmol/g pro) |
|---|---|---|
| Control | 181.28 ± 7.21 | 31.25 ± 3.97 |
| 12.5 mg/kg MnCl2 | 335.34 ± 19.47∗∗ | 25.88 ± 6.15∗∗ |
| 25 mg/kg MnCl2 | 354.63 ± 8.71∗∗ | 19.07 ± 6.63∗∗ |
| 50 mg/kg MnCl2 | 390.18 ± 10.51∗∗ | 13.88 ± 3.39∗∗ |
| 500 mg/kg AAH + 50 mg/kg MnCl2 | 415.98 ± 12.44∗∗# | 5.83 ± 1.19∗∗# |
| 75 mg/kg SSZ + 50 mg/kg MnCl2 | 410.27 ± 9.38∗∗# | 5.92 ± 1.5∗∗# |
| 100 mg/kg NAC + 50 mg/kg MnCl2 | 344.73 ± 8.91∗∗## | 19.84 ± 4.69∗∗# |
Data are mean ± SD; n = 6 each. ∗∗p < 0.01 denote statistical significance compared with the control group; #p < 0.05, ##p < 0.01 denote statistical significance compared with the MnCl2 alone group.