Table 4.
Relation of changes over time in knee pain-related outcomes to mood, sleep, well-being, and quality of life and to pain-related fear and catastrophizing in older adults with symptomatic osteoarthritis of the knee.
| Change from baseline | Change over time at 2 months | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| KOOS Total-WOMAC | KOOS Function | KOOS Symptoms | KOOS Pain | KOOS Sport | KOOS QOL | NRS Pain now | NRS Pain average | NRS Pain worst | NRS Pain least | PGA | |
| Stress, sleep, mood, and QOL | |||||||||||
| Perceived stress (PSS) | 0.39( ∗ ) | ||||||||||
| Mood (Profile of Mood States: total score) | 0.38( ∗ ) | 0.42( ∗ ) | 0.47∗ | 0.39( ∗ ) | |||||||
| Sleep Quality (Pittsburgh Sleep Quality Index) | |||||||||||
| Total Score | 0.41 ( ∗ ) | 0.40( ∗ ) | |||||||||
| Mean number hours sleep | -0.40( ∗ ) | -0.46∗ | -0.47∗ | -0.52∗∗ | |||||||
| Health related Quality of Life (SF-36) | |||||||||||
| Mental Health component | -0.53∗∗∗ | -0.61ŧ | -0.46∗ | -0.43∗ | -0.49∗∗ | ||||||
| Physical Health component | -0.53∗ | -0.53∗∗ | -0.39( ∗ ) | -0.44∗ | -0.47∗ | 0.39( ∗ ) | |||||
| Pain-related Fear/Catastrophizing | |||||||||||
| Tampa Scale Kinesiophobia (total score) | 0.52∗∗ | 0.52∗∗ | 0.51∗∗ | 0.41( ∗ ) | 0.44∗ | 0.63† | 0.56∗∗∗ | 0.55∗∗∗ | |||
| Pain Catastrophizing Scale (total score) | 0.54∗∗∗ | ||||||||||
Abbreviations: NRS=Numerical Rating Scale; PGA=Patient Global Assessment; QOL=quality of life.
(∗) p<0.1, ∗p<0.05; ∗∗p <0.025; ∗∗∗p<0.01; ŧp<0.005.