Table 1.
Clinical-pathological characteristics of the patients enrolled in the study.
| RF | TACE | TOTAL | p | |
|---|---|---|---|---|
| Patients characteristics | ||||
|
| ||||
| Male / Female | 11/4 | 11/3 | 22/7 | ns |
| Age | 72 ± 5 | 68 ± 10 | 70 ± 8 | 0.010 |
| Etiologies | 15 | 14 | 29 | ns |
| Alcohol/metabolic | 9 | 7 | 16 | |
| Alcohol | 1 | 3 | 4 | |
| HCV | 5 | 4 | 9 | |
|
| ||||
| Clinical characteristics | ||||
|
| ||||
| CTP A/B | 10/0 | 15/4 | 25/4 | 0.042 |
| BCLC 0/A/B | 2/10/3 | 2/5/7 | 4/15/10 | ns |
| Milan criteria (in/out) | 13/1 | 8/3 | 21/4 (unknown 4) | ns |
| Up-to-7 criteria (in/out) | 14/0 | 9/2 | 23/2 (unknown 4) | ns |
| Largest nodule diameter (mm) | 29 ± 10 | 27 ± 7 | 28 ± 9 | ns |
| Total tumor volume (cm3) | 18 ± 24 | 22 ± 25 | 20 ± 24 | ns |
|
| ||||
| Laboratory finding | ||||
|
| ||||
| Creatinine (mg/dl) | 0.9 ± 0.3 | 0.8 ± 0.2 | 0.9 ± 0.2 | ns |
| Sodium (mmol/l) | 136.0 ± 2.2 | 138.4 ± 2.6 | 138.0 ± 2.4 | ns |
| Total bilirubin (mg/dl) | 0.94 ± 0.33 | 1.33 ± 0.93 | 1.12 ± 0.68 | 0.033 |
| Total protein (g/dl) | 7.2 ± 0.5 | 7.4 ± 0.7 | 7.2 ± 0.6 | ns |
| Albumin (g/dl) | 3.8 ± 0.4 | 3.6 ± 0.3 | 3.7 ± 0.3 | ns |
| AST (IU/l) | 77.7 ± 79.7 | 46.7 ± 24.3 | 63.9 ± 62.5 | 0.001 |
| ALT (IU/l) | 80.3 ± 96.7 | 37.4 ± 19.4 | 61.2 ± 75.3 | 0.001 |
| ALP (IU/l) | 101.3 ± 44.1 | 101.8 ± 40.7 | 101.5 ± 41.8 | ns |
| GGT (IU/l) | 112.4 ± 109 | 135.3 ± 146.5 | 123.4 ± 126.7 | ns |
| WBC (103/μl) | 5.1 ± 2.1 | 4.8 ± 2.1 | 4.97 ± 2.07 | ns |
| Hemoglobin (g/dl) | 13.5 ± 2.1 | 13.7 ± 1.5 | 13.6 ± 1.8 | ns |
| Hematocrit (%) | 40.4 ± 5.7 | 40.6 ± 4.3 | 40.5 ± 4.9 | ns |
| Platelets (103/μl) | 135.7 ± 80 | 102.6 ± 55.3 | 119.7 ± 70.2 | ns |
| AFP (ng/ml) | 20 ± 30.7 | 18.5 ± 23.3 | 19.3 ± 26.8 | ns |
| INR | 1.12 ± 0.1 | 1.18 ± 0.1 | 1.14 ± 0.12 | ns |
HCV: hepatitis C virus, CTP: Child-Turcotte-Pugh, BCLC: Barcelona Clinic Liver Cancer, AST: aspartate aminotransferase, ALT: alanine aminotransferase, ALP: alkaline phosphatase, GGT: gamma glutamyl transferase, WBC: white blood cells, AFP: alpha fetoprotein, INR: international normalized ratio, and ns: not significant