Table 2.

Description and values of parameters used.

Parameter	Description	Value	Reference
β w	Transmission rate of wild-type strain	0.00102 day−1	Estimated
β r	Transmission rate of resistant strain	0.00026 day−1	Estimated
ε	Vaccine efficacy	0.77	[58]
ϕ	Vaccination rate	0.00027375 day−1	[59]
b	Rate of developing drug resistance	0.118	Estimated
α	Recovery rate for individuals in Iw class	0.1998 day−1	[6]
α r	Recovery rate for individuals in IR class	0.0714 day−1	Estimated
ϑ	Rate of losing immunity	0.00833 day−1	[34]
a w	Death rate due to infection with wild-type strain	0.01	[39]
$\frac{1}{\mu }$	Average human lifespan	70 × 365 days	Estimated
π	Recruitment rate	0.0381	Estimated
a r	Death rate due to infection with resistant strain	0.021	Estimated