Ingenol mebutate in the treatment of actinic keratoses. 1: complete clearance in a patient with AK on left frontal region. Clinical grade decreased from III (a, pretreatment) to 0 (b, posttreatment); dermoscopic grade decreased from III (c, pretreatment) to 0 (d, posttreatment). 2: partial clearance in a patient with AK on left frontotemporal region. Clinical grade decreased from III (a, pretreatment) to I (b, posttreatment); dermoscopic grade decreased from III (c, pretreatment) to II (d, posttreatment). 3: lack of response in a patient with AK on the scalp. Clinical and dermoscopic grade remained stable at III (a-c, pretreatment; b-d, posttreatment).