Table 4.
Specimens, diagnostic method and reported but unverified antibiotic susceptibility test results in 42 culture-confirmed melioidosis cases with available clinical data from 2012 to 2017.
Characteristics | Total (n = 42) |
---|---|
Specimens * | |
Blood | 25 (60%) |
Pus | 8 (19%) |
Urine | 7 (17%) |
Tissue ** | 2 (5%) |
Sputum | 1 (2%) |
Diagnostic method | |
Vitek 2 identification system | 37 (88%) |
Microgen | 5 (12%) |
Antibiotic susceptibility test | |
Not done | 27 (64%) |
Done *** | |
Gentamicin (S) | 0/13 (0%) |
Amoxicillin-clavulanic acid (S) | 2/5 (40%) |
Ceftazidime (S) | 12/14 (86%) |
Doxycycline (S) | 7/9 (78%) |
Meropenem (S) | 14/15 (93%) |
Imipenem (S) | 2/2 (100%) |
Trimethoprim-sulfamethoxazole (S) | 6/7 (86%) |
* One adult patient had two culture-positive specimens. ** Tibial tissue (1), scrotal tissue (1). *** Data are number of isolates demonstrating susceptibility to the antimicrobial over the total number of isolates tested (%). Data are from the microbiology laboratories that had isolated B. pseudomallei from clinical specimens. Some AST results were not typical for B. pseudomallei, including resistance to amoxicillin-clavulanic acid, ceftazidime, doxycycline, meropenem and trimethoprim-sulfamethoxazole. We note that the AST results may be inaccurate or some isolates might not actually be B. pseudomallei.