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. Author manuscript; available in PMC: 2018 Sep 13.
Published in final edited form as: Brain Stimul. 2018 Jan 31;11(3):575–581. doi: 10.1016/j.brs.2018.01.029

Fig. 1. Cortical thickness change correlates with clinical improvement.

Fig. 1.

A. A cortex-wide analysis revealed a significant correlation between cortical thickness change in left rostral anterior cingulate cortex (rACC) and improvement in depression symptoms. The peak correlation is significant at P < 0.001 uncorrected. Findings are shown at P < 0.01 to display the extent of the spatial distribution of the correlation, also see Fig. S3 showing these results at a P < 0.001 threshold. B. Average cortical thickness changes within this rACC region differ between responders and non-responders (+0.074 and −0.095 mm, respectively; P < 0.05) with non-responders showing a significant reduction in cortical thickness (P < 0.01). C. A scatter plot shows the correlation between change in cortical thickness within this ROI and clinical response (r = 0.4, P < 0.01). *P < 0.05, **P < 0.01.