Figure 2: C–H Functionalization with benzamide 1a, butadiene and diverse aldehydes 3.
Reactions were performed on 0.2 mmol scale with 1a at [0.4 M] and proceeded with >98:2 dr unless otherwise noted. Isolated yields of product after purification by chromatography are reported. See Supplementary Methods for experimental details. a. Reaction performed with 5 mol % of (Co(III)L) and 20 mol % of pivalic acid in place of acetic acid. b. Reaction performed with 1a at [1.0 M] and at 70 °C.