Fig 1. Schematic representation of TRPM5-positive MVCs and SCCs.

Previously known molecular markers and innervation pattern are represented. We report here the presence in MVCs of other SCC transduction signaling cascade elements: gustducin, PLCβ2, and T1R3 (underlined). Other than a few morphological differences and the fact that MVCs are not innervated by peptidergic trigeminal nerve fibers, SCCs and MVCs are the same cell type in two different locations of the nasal cavity.