Table 1. Probabilities, symptoms and symptom score related to fibromyalgia according to gender among RA patients in the National Data Bank for Rheumatic Diseases (S2 File).
| Females: Probability (%) or Mean (S.E.) | Males: Probability (%) or Mean (S.E.) | Differences in Probability (%) or Mean (CI) | Cases: % Female | |
|---|---|---|---|---|
| Number of participants | 2,171 | 2,171 | ||
| Diagnostic variables | ||||
| Fibromyalgia % | 22.1% | 15.6% | 6.5% (4.2, 8.9%) | 58.7% |
| Generalized pain % | 36.8% | 32.4% | 4.4% (1.5, 7.3%) | 53.2% |
| WPI (0–19) | 5.9 | 4.9 | 1.0 (0.7, 1.3) | |
| SSS (0–12) | 4.3 | 3.4 | 0.9 (0.7, 1.1) | |
| Depression % | 23.6 | 19.0 | 4.6 (2.2, 7.1%) | |
| Headache % | 29.9 | 17.6 | 11.3 (8.8, 13.8%) | |
| Abdominal pain % | 16.2 | 9.4 | 6.8 (4.8, 8.8%) | |
| PSD (0–31) | 10.2 (1.6) | 8.2 (1.6) | 2.0 (2.2) | |
| Symptom variables | ||||
| Dry eyes % | 46.6 | 30.1 | 16.5 (13.6, 19.4%) | |
| Bruising % | 42.6 | 30.4 | 12.2 (9.3, 15.1%) | |
| Dry mouth % | 37.3 | 25.2 | 12.1 (9.3, 14.9%) | |
| Paresthesias % | 46.2 | 37.3 | 8.9 (5.911.8%) | |
| Epigastric pain % | 19.1 | 10.3 | 8.8(6.7, 10.9%) | |
| Nausea % | 18.5 | 10.3 | 8.2 (6.1, 10.3%) | |
| Heartburn % | 26.5 | 19.0 | 7.5 (5.0, 10.0%) | |
| Dizziness % | 21.9 | 14.8 | 7.1 (5.0, 9.5%) | |
| “Nerves” % | 23.2 | 16.2 | 7.0, (4.7, 9.4%) | |
| Oral Ulcers % | 14.0 | 7.8 | 6.0 (4.2, 7.9) | |
| Reynaud’s | 11.3 | 5.9 | 5.5 (3.8, 7.2%) | |
| Diarrhea % | 16.6 | 12.2 | 4.9 (2.5, 6.7%) | |
| Vision problems % | 29.4 | 25.4 | 4.0 (1.4, 6.7%) | |
| Photo-sensitivity % | 11.8 | 9.3 | 2.6 (0.6, 4.4%) | |
| Hives % | 4.6 | 2.6 | 2.0 (0.9, 3.2%) | |
| Rash % | 9.7 | 8.1 | 1.6 (0.1, 3.0%) | |
| Dyspnea % | 16.5 | 14.0 | 0.2 (-1.0, 3.8%) | |
| Pleurisy % | 5.7 | 5.7 | 0.0 (-1.3, 1.5%) | |
| Asthma % | 14.3 | 18.9 | -1.4 (-3.6, 0.7%) | |
| Tinnitus % | 23.8 | 31.4 | -7.6 (-10.4, -4.9%) | |
| Hearing problem % | 20.8 | 31.0 | -10.2 (-12.9, -7.7%) | |
| Total symptom count | 4.7 | 3.7 | 1.0 (0.8, 1.2) | |
| Clinical scores | ||||
| VAS Pain (0–10) | 3.9 | 3.4 | 0.4 (0.3, 0.6) | |
| Patient global (0–10) | 3.8 | 3.5 | 0.3 (0.1, 0.4) | |
| VAS Fatigue (0–10) | 4.3 | 3.4 | 0.9 (0.7, 1.0) | |
| HAQ disability (0–3) | 1.1 | 0.7 | 0.4 (0.3, 0.4) | |
| SF-36 MCS | 48.4 | 49.2 | -0.7 (-1.4, -0.3) | |
| SF-36 PCS | 36.4 | 39.6 | -3.2 (-3.9, -2.5) |
WPI = Widespread pain index; SSS = Symptom severity scale; PSD = Polysymptomatic distress; VAS = Visual analog scale; HAQ = Health assessment questionnaire; SF-36 MCS = Short form 36