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. 2018 Sep 13;13(9):e0203746. doi: 10.1371/journal.pone.0203746

Table 3. Instrumental variable regressions comparing IV and oral acetaminophen patients*.

Difference 95% Confidence Interval p-value
Length of Stay (days) -0.80 -0.92 -0.68 <0.0001
Hospitalization Cost ($) -2,449.0 -2902.4 -1995.6 <0.0001
Morphine Equivalent Dose (mg) -1.41 -3.43 0.61 0.17

*Two-stage least squares with quarterly rate of IV acetaminophen use at the hospital as the instrument. Adjusted for patient age, gender, race, APR-DRG Severity of Illness and Risk of Mortality, year of admission, admitting physician type, hospital type (academic), hospital location (urban/rural), and number of beds. Oral Acetaminophen is the reference group.