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. 2018 Sep 13;13(9):e0203789. doi: 10.1371/journal.pone.0203789

Table 1. Characteristics of each group.

Group 1
(inverted ILM flap)
Group 2
(ILM peeling)
P value
Number of eyes 46 44
Age (years) 65.6 ± 8.1 65.5 ± 11.3 0.97
Sex (F:M) 27 : 19 32 : 12 0.16
Laterality (R:L) 18 : 28 20 : 24 0.54
MH duration (months) 7.8 ± 18.3 7.9 ± 36.4 0.98
Procedure 0.23
    Vitrectomy with cataract surgery 40 34
    Only vitrectomy 6 10
IOP (mmHg) 14.7 ± 4.0 15.0 ± 3.5 0.53
Axial length (mm) 24.2 ± 1.8 24.4 ± 2.3 0.72
MH diameter (μm) 491.5 ± 135.9 465.9 ± 129.5 0.36
MH stage (1:2:3:4) 0:5:5:36 1:7:5:31 0.56
MH closure success: failure 46 : 0 41 : 3 0.04
VA (logMAR)
    Preoperative 0.8 ± 0.3 0.7 ± 0.3 0.06
    1M-postoperative 0.5 ± 0.3 0.4 ± 0.4 0.25
    6M-postoperative 0.4 ± 0.3 0.3 ± 0.3 0.42
OCT findings
    1M-postoperative IS/OS disruption (n, %) 41, 89 33, 75 0.13
    6M-postoperative IS/OS disruption (n, %) 14, 30 22, 50 0.80
    1M-postoperative ELM disruption (n, %) 26, 57 16, 36 0.08
    6M-postoperative ELM disruption (n, %) 7, 15 12, 27 0.72

ILM = internal limiting membrane, MH = macular hole, IOP = intraocular pressure, VA = visual acuity, logMAR = logarithm of minimum angle of resolution, OCT = optical coherence tomography, IS/OS = photoreceptor inner and outer segment, ELM = external limiting membrane