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. 2018 Sep 13;13(9):e0203893. doi: 10.1371/journal.pone.0203893

Fig 3. Open chromatin and transcription factor occupancy in functional CpG sites.

Fig 3

Pie charts depicting H3K27Ac histone mark layering, location of CpG sites and transcription factor binding sites. A) The layering of H3K27Ac histone mark conferring an open chromatin status was seen in 87% of sites. B) 57% of the 64 sites were occupied by RNA polymerase II subunit RPB1. C) 57% of 64 differentially methylated functional CpG sites were in the promoter region of genes. See S2 Table for confirmation data per each gene.