Table 2A.
IL-17A through IL-17F expression in two pooled independent cohorts of Sézary patients with RNA-Sequencing gene expression data (Ungewickell et al., Choi et al.).
| Genes | Ratio mean TPM SS/ mean TPM Control | Fraction Genes with TPM > GOI – Control | Fraction Genes with TPM > GOI – SS | Corrected p-value |
|---|---|---|---|---|
| IL-17A | >63.21 | 1 | 0.2981 | < 10−5 |
| IL-17B | 0.89 | 0.1583 | 0.2443 | < 10−5 |
| IL-17C | 5.47 | 0.6564 | 0.4476 | < 10−5 |
| IL-17D | 79.15 | 0.5131 | 0.2735 | < 10−5 |
| IL-17E | >251.28 | 1 | 0.2292 | < 10−5 |
| IL-17F | >24.65 | 1 | 0.4160 | < 10−5 |
TPM = Transcripts per Million, GOI = Gene-Of-Interest (Tested gene), SS = Sézary Syndrome.