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. 2018 Aug 28;7:e36607. doi: 10.7554/eLife.36607

Figure 6. Effect of SC lesion on STN nociceptive responses.

Figure 6.

(A) Coronal sections (stained with cresyl violet) of the SC following a unilateral injection of ibotenic acid (dotted line, left) and its control contralateral side (right). Scale bars = 500 µm. (B) Schematic of a typical lesion (in gray) with ibotenic acid in the SC. (C) Plot of STN phasic noxious evoked responses in the STN according to their duration and latency in control (white) and SC lesioned (black) animals. The box outlined with a dotted line highlights the absence of long-duration responses in SC lesioned rats. (D) Table showing the proportions of different STN nociceptive response types in control and SC-lesioned animals. Note that the proportion of STN long-lasting responses decreases in SC-lesioned animals.