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. 2018 Aug 28;7:e36607. doi: 10.7554/eLife.36607

Figure 7. Effect of PBN lesion on STN nociceptive responses.

Figure 7.

(A) Schematic of the ibotenic acid lesion of the PBN. Each individual lesion is illustrated in a different tone of gray. (B) Coronal sections (stained with cresyl violet) of the parabrachial nucleus following a unilateral injection of ibotenic acid (dotted line, top) and its control contralateral side (bottom). Scale bars = 500 µm. (C) Plot of STN phasic noxious-evoked responses in the STN according to their duration and latency in control (white) and PBN-lesioned (black) animals. Note that PBN lesion abolished all types of STN nociceptive response. (D) Table showing the proportion of STN nociceptive response types in control and PBN-lesioned animals.