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. 2018 Sep 7;13:5231–5248. doi: 10.2147/IJN.S167142

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Intracerebral distribution of MSC NPs.

Notes: (A) Confocal laser-scanning microscopy of glioma. All the area was within the glioma. (B) Brain tissue at the therapeutic injection site 2 days after contralateral injection of MSC NPs. MSCs were incubated with 8 ng/mL Ptx-PLGA NPs for 8 hours, and labeled with a red fluorescent probe – CM-Dil. Nuclei were stained with DAPI before observation.

Abbreviations: Ptx-PLGA NPs, paclitaxel poly(d,l-lactide-co-glycolide) nanoparticles; MSC, mesenchymal stem cell.