Table 1.
SIRs and 95% CIs comparing observed cancers in PLWHA to expected counts from the US general population, according to cancer diagnosis and stage
| Overall |
Local stage |
Regional stage |
Distant stage |
Unknown stage |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cancer diagnosis | No. | SIR (95% CI) | No. (%) | SIR (95% CI) | No. (%) | SIR (95% CI) | No. (%) | SIR (95% CI) | No. (%) | SIR (95% CI) |
| Invasive breast cancer | 688 | 0.63 (0.58 to 0.68) | 336 (48.8)* | 0.58 (0.52 to 0.64) | 254 (36.9) | 0.61 (0.54 to 0.69) | 68 (9.9) | 0.94 (0.73 to 1.20) | 30 (4.4) | 1.01 (0.68 to 1.45) |
| Estrogen receptor positive | 305 | 0.55 (0.49 to 0.61) | 166 (54.4) | 0.54 (0.46 to 0.63) | 114 (37.4) | 0.55 (0.45 to 0.65) | 24 (7.9) | 0.74 (0.48 to 1.05) | 1 (<1) | 0.23 (0.01 to 1.28) |
| Estrogen receptor negative | 164 | 0.68 (0.58 to 0.79) | 73 (44.5) | 0.59 (0.47 to 0.75) | 69 (42.1) | 0.71 (0.55 to 0.89) | 21 (12.8) | 1.10 (0.68 to 1.68) | 1 (<1) | 0.42 (0.01 to 2.36) |
| Prostate cancer | 1522 | 0.48 (0.46 to 0.51) | 1242 (81.6) | 0.49 (0.46 to 0.52) | 132 (8.7) | 0.40 (0.33 to 0.47) | 61 (4.0) | 0.55 (0.42 to 0.71) | 87 (5.7) | 0.40 (0.33 to 0.47) |
| Proximal colon cancer | 269 | 0.67 (0.59 to 0.75) | 95 (35.3) | 0.69 (0.56 to 0.85) | 97 (36.1) | 0.62 (0.50 to 0.75) | 67 (24.9) | 0.69 (0.54 to 0.88) | 10 (3.7) | 0.81 (0.39 to 1.50) |
| Distal colon cancer | 173 | 0.51 (0.43 to 0.59) | 62 (35.8) | 0.49 (0.37 to 0.62) | 61 (35.3) | 0.50 (0.38 to 0.64) | 40 (23.1) | 0.51 (0.37 to 0.70) | 10 (5.8) | 0.71 (0.34 to 1.31) |
| Rectal cancer | 271 | 0.69 (0.61 to 0.77) | 106 (39.1) | 0.66 (0.54 to 0.80) | 75 (27.7) | 0.60 (0.47 to 0.75) | 55 (20.3) | 0.74 (0.56 to 0.97) | 35 (12.9) | 1.02 (0.71 to 1.42) |
*
Percentage of overall cancer diagnoses by stage. CI = confidence interval; PLWHA = people living with HIV or AIDS; SIR = standardized incidence ratio.