Table 2.
SIRs and 95% CIs comparing observed cancers in PLWHA to expected counts from the general US population, according to cancer diagnosis and tumor size
| Overall |
Small tumors <2 cm |
Medium tumors 2–4.9 cm |
Large tumors >5 cm |
|||||
|---|---|---|---|---|---|---|---|---|
| Cancer diagnosis | No. | SIR (95% CI) | No. (%) | SIR (95% CI) | No. (%) | SIR (95% CI) | No. (%) | SIR (95% CI) |
| Invasive breast cancer | 688 | 0.63 (0.58 to 0.68) | 256 (37.2)* | 0.56 (0.49 to 0.63) | 176 (25.6) | 0.61 (0.52 to 0.70) | 64 (9.3) | 0.65 (0.50 to 0.83) |
| Proximal colon cancer | 269 | 0.67 (0.59 to 0.75) | 26 (9.7) | 0.72 (0.47 to 1.06) | 79 (29.4) | 0.73 (0.58 to 0.91) | 79 (29.4) | 0.63 (0.50 to 0.78) |
| Distal colon cancer | 173 | 0.51 (0.43 to 0.59) | 25 (14.5) | 0.67 (0.43 to 0.99) | 42 (24.3) | 0.46 (0.33 to 0.62) | 41 (23.7) | 0.51 (0.36 to 0.69) |
| Rectal cancer | 271 | 0.69 (0.61 to 0.77) | 41 (15.1) | 0.67 (0.48 to 0.91) | 60 (22.1) | 0.75 (0.57 to 0.97) | 43 (15.9) | 0.62 (0.45 to 0.83) |
*
Percentages of overall cancer diagnoses by tumor size calculated among cases from 2004 onward, when tumor size data were available from all registries except Colorado (breast: 574, proximal colon: 232, distal colon: 145, rectum: 223). Missing tumor size data by diagnosis: breast (14%), prostate (100%), proximal colon (21%), distal colon (26%), rectum (35%). CI = confidence interval; PLWHA = people living with HIV or AIDS; SIR = standardized incidence ratio.