Table 1.
Characteristics of participants who completed a baseline survey and agreed to random assignment to phone or in-person (usual care) disclosure of genetic test results
| Characteristic | Telephone disclosure (n = 401) | In-person disclosure (n = 418) |
|---|---|---|
| Mean age (SD), y | 48.20 (12.54) | 48.96 (12.88) |
| Sex, No. (%) | ||
| Female | 374 (93.3) | 385 (92.1) |
| Male | 27 (6.7) | 33 (7.9) |
| Race, No. (%) | ||
| White | 340 (84.8) | 341 (81.6) |
| Nonwhite | 61 (15.2) | 77 (18.4) |
| Ashkenazi Jewish, No. (%) | ||
| Yes | 56 (14.0) | 71 (17.0) |
| No | 274 (68.3) | 284 (67.9) |
| Not captured | 71 (17.7) | 63 (15.1) |
| Education, No. (%) | ||
| Some college or less | 166 (41.4) | 164 (39.2) |
| College degree or more | 234 (58.4) | 251 (60.0) |
| Missing | 1 (<1) | 3 (<1) |
| Household income, yearly, No. (%) | ||
| $49 999 or less | 86 (21.4) | 97 (23.2) |
| $50 000–$99 999 | 101 (25.2) | 112 (26.8) |
| $100 000–$149 999 | 75 (18.7) | 69 (16.5) |
| $150 000 or more | 85 (21.2) | 81 (19.4) |
| Missing | 54 (13.5) | 59 (14.1) |
| Marital status, No. (%) | ||
| Married/domestic partner | 284 (70.8) | 285 (68.2) |
| Not currently married/in a domestic partnership | 117 (29.2) | 133 (31.8) |
| Personal history of cancer, No. (%) | ||
| No | 193 (48.1) | 188 (45.0) |
| Yes | 208 (51.9) | 230 (55.0) |
| Breast, No. (%) | 154 (74.0) | 160 (70.0) |
| Ovary, No. (%) | 21 (10.1) | 30 (13.0) |
| Single primary, nonbreast/ovary, No. (%) | 22 (10.6) | 27 (11.7) |
| Multiple primaries, No. (%) | 11 (5.3) | 13 (5.7) |
| Testing for surgical treatment decision, No. (%) | ||
| Yes | 32 (8.0) | 25 (6.0) |
| No | 369 (92.0) | 393 (94.0) |
| Known genetic mutation in family, No. (%) | ||
| Yes | 91 (22.7) | 95 (22.7) |
| No | 310 (77.3) | 323 (77.3) |
| Number of FDR/SDR with cancer, mean (SD) | 3.63 (2.27) | 3.79 (2.39) |
| Had multigene testing, No. (%) | ||
| Yes | 110 (27.4) | 121 (28.9) |
| No | 87 (21.7) | 93 (22.2) |
| NA (recruited prior to inclusion of multigene testing) | 204 (50.9) | 204 (48.8) |
| Result, No. (%) | ||
| Positive | 51 (12.7) | 57 (13.6) |
| Variant of uncertain significance | 36 (9.0) | 40 (9.6) |
| Negative | 249 (62.1) | 261 (62.4) |
| True negative | 51 (12.7) | 44 (10.5) |
| Testing canceled | 12 (3.0) | 7 (1.7) |
| Participant declined/unable to receive results | 2 (<1) | 9 (2.2) |
| Recruitment site, No. (%) | ||
| University of Pennsylvania | 103 (275.7) | 108 (25.8) |
| Fox Chase Cancer Center | 150 (37.4) | 150 (35.9) |
| University of Chicago | 76 (19.0) | 85 (20.3) |
| John H. Stroger Jr. Hospital at Cook County | 26 (6.5) | 24 (5.7) |
| MD Anderson at Cooper University Hospital | 46 (11.5) | 51 (12.2) |
| Distance to site*, mean (SD) | 37.47 (161.77) | 34.24 (127.23) |
*
Straight-line distance was calculated using participant ZIP code and the corresponding site ZIP code to represent travel distance for participants. FDR=First Degree Relative; SDR=Second Degree Relative.
†
There were no statistically significant differences between randomized group when including only the subset with paired data.