Table 3.
Relative risk ratios (RRR) and 95% bootstrapped confidence intervals for effect of covariates on transitions from disengaged states to continued disengagement or death, relative to remaining engaged in care.
| Prior state | Disengaged 1 | Disengaged 2 | Disengaged 3+ | |||
|---|---|---|---|---|---|---|
| Current state | Disengaged 2 | Death | Disengaged 3+ | Death | Disengaged 3+ | Death |
| CD4 counts (Ref: <250) | ||||||
| 250–500 | 0.97 (0.91, 1.05) |
0.38
(0.30, 0.48) |
1.18
(1.05, 1.33) |
0.51 (0.348, 0.739) |
1.19
(1.08, 1.32) |
0.63
(0.53, 0.75) |
| >500 |
0.83
(0.77, 0.89) |
0.18
(0.13, 0.24) |
1.15
(1.01, 1.30) |
0.26
(0.16, 0.40) |
1.10 (0.99, 1.23) |
0.49
(0.40, 0.59) |
| never measured |
5.39
(4.35, 6.87) |
2.68
(1.61, 4.56) |
3.22
(2.32, 4.78) |
1.26 (0.61, 2.60) |
2.94
(2.29, 3.94) |
1.50
(1.06, 2.14) |
| Viral load (VL) measured |
0.59
(0.51, 0.67) |
0.25
(0.16, 0.38) |
0.53
(0.40, 0.69) |
0.11
(0.05, 0.23) |
0.28
(0.22, 0.35) |
0.14
(0.10, 0.185) |
| log10 VL among measured |
1.04
(1.02, 1.06) |
1.27
(1.18, 1.35) |
0.96
(0.92, 0.99) |
1.24
(1.11, 1.41) |
1.06
(1.03, 1.10) |
1.26
(1.19, 1.33) |
| Initiated ART | 1.04 (0.92, 1.17) |
0.70
(0.49, 0.99) |
1.14
(0.95, 1.35) |
0.78
(0.49, 1.35) |
1.19
(1.02, 1.40) |
1.11 (0.87, 1.45) |
| Year initiated ART (Ref: 1996–2002) | ||||||
| 2003–2006 | 0.98 (0.89, 1.08) |
1.40
(1.03, 1.94) |
0.88 (0.75, 1.05) |
0.85 (0.52, 1.27) |
0.59
(0.52, 0.68) |
0.72
(0.56, 0.90) |
| 2007–2010 |
0.82 (0.73, 0.93) |
1.19 (0.76, 1.90) |
0.67
(0.54, 0.86) |
0.95 (0.48, 1.66) |
0.24
(0.20 0.29) |
0.35
(0.22, 0.53) |
| 2011+ |
0.62
(0.52, 0.74) |
0.60 (0.25, 1.36) |
0.36
(0.26, 0.50) |
0.67 (0.11, 1.92) |
0.05
(0.04, 0.07) |
0.17
(0.05, 0.34) |
| Missing ART information |
2.55
(2.18, 3.07) |
2.72
(1.62, 4.36) |
2.48
(1.93, 3.41) |
2.32
(1.25, 4.55) |
3.03
(2.39, 3.90) |
2.92
(2.07, 4.16) |
| AIDS-defining illness |
0.79
(0.73, 0.85) |
2.54
(2.03, 3.13) |
0.72
(0.64, 0.81) |
1.65
(1.16, 2.34) |
0.47
(0.41, 0.52) |
0.72
(0.59, 0.88) |
| Race (Ref: Caucasian) | ||||||
| African American |
0.84 (0.79, 0.90) |
0.712
(0.57, 0.90) |
0.77
(0.69, 0.86) |
0.92 (0.67, 1.31) |
0.72
(0.65, 0.78) |
0.94 (0.79, 1.10) |
| Others | 0.96 (0.87, 1.08) |
0.99 (0.61, 1.50) |
0.89 (0.74, 1.09) |
0.65 (0.24, 1.22) |
1.08 (0.93, 1.26) |
0.90 (0.59, 1.26) |
| Missing |
1.34
(1.11, 1.66) |
1.46 (0.48, 3.14) |
1.38
(1.00, 2.01) |
1.25 (0.22, 3.05) |
1.67
(1.26, 2.25) |
1.01 (0.50, 1.80) |
| Hispanic ethnicity | 0.96 (0.87, 1.07) |
0.50
(0.28, 0.79) |
0.90 (0.75, 1.08) |
0.52
(0.25, 0.91) |
0.98 (0.84, 1.15) |
0.71
(0.49, 0.98) |
| Missing ethnicity |
1.43
(1.20, 1.73) |
2.32
(1.20, 3.98) |
2.70 (2.03, 3.77) |
4.29
(1.74, 8.66) |
2.13
(1.74, 2.68) |
3.15
(2.14, 4.48) |
| Age>40yrs | 0.98 (0.92, 1.03) |
2.04 (1.66, 2.53) |
1.04 (0.94, 1.14) |
1.93
(1.42, 2.71) |
1.25
(1.16, 1.36) |
2.27
(1.92, 2.71) |
| Sex & HIV risk factors (Ref: MSM NIDU) | ||||||
| MSM IDU | 1.02 (0.90, 1.16) |
1.62
(1.05, 2.41) |
0.83 (0.69, 1.01) |
1.24 (0.65, 2.23) |
0.77
(0.65, 0.91) |
1.38
(1.01, 1.92) |
| Male hetero NIDU |
0.89 (0.80, 0.98) |
1.12 (0.80, 1.52) |
0.75
(0.64, 0.86) |
1.26 (0.77, 1.97) |
0.82
(0.72, 0.95) |
0.94 (0.72, 1.21) |
| Male hetero IDU | 1.12 (0.96, 1.28) |
1.97 (1.27, 2.99) |
0.75
(0.59, 0.97) |
1.77 (0.87, 3.31) |
0.63
(0.51, 0.77) |
1.17 (0.83, 1.63) |
| Female hetero NIDU | 1.01 (0.92, 1.10) |
1.07 (0.77, 1.46) |
0.86
(0.74, 0.99) |
1.43 (0.89, 2.33) |
0.81
(0.73, 0.92) |
0.73
(0.56, 0.94) |
| Female hetero IDU | 0.89 (0.76, 1.04) |
1.80
(1.10, 2.81) |
1.03 (0.78, 1.41) |
1.97 (0.78, 3.97) |
0.69
(0.55, 0.87) |
1.71
(1.18, 2.50) |
| Others | 1.07 (0.99, 1.16) |
1.49
(1.13, 1.97) |
0.90 (0.79, 1.02) |
1.37 (0.92, 2.10) |
0.78
(0.70, 0.87) |
1.38
(1.13, 1.69) |
| Missing |
1.25
(1.07, 1.48) |
1.52 (0.81, 2.53) |
1.21 (0.88, 1.72) |
3.89
(1.98, 7.66) |
1.76
(1.36, 2.32) |
2.93
(2.06, 4.37) |