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肺切除前胸腔冲洗液细胞学检查阳性结果的相关因素
Factors associated with positive pre-resectional PLC
| Author, ref.number, year, type of study | Patient group and saline volume for washing | Factors associated with positive pre-resectional PLC (P value) |
| PLC: pleural lavage cytology. | ||
| Shintani et al[8] (2008) Prospective study | Total number of patients: 1, 271 Patients with positive PLC before lung resection: 67 (5.3%) 500 mL physiologic saline solution | Pathologic stage (P=0.039, 7) Pathologic pleural involvement (P＜0.000, 1) Pathologic T status (P=0.000, 2) Vascular invasion (P=0.004, 8) |
| Taniguchi et al[13] (2009) Prospective study | Total number of patients: 296 Patients with positive PLC after thoracotomy: 14 (4.7%) 50 mL warm physiologic saline solution | T stage (P=0.028) Pleural invasion (P＜0.000, 1) Lymphatic invasion (P=0.002) N stage (P=0.369) Vascular invasion (P=0.176) |
| Kaneda et al[18] (2011) Retrospective study | Total number of patients: 3, 231 Patients with positive PLC immediately after thoracotomy: 148 (4.58%) Physiological saline of ≤100 mL | Histology (adenocarcinoma) (P=0.015) Pathological stage (P < 0.001) Pathological T score (P < 0.001) Pathological N score (P < 0.001) Pleural invasion (P < 0.001) |
| Yanagawa et al[19] (2014) Prospective study | Total number of patients: 428 Patients with positive PLC immediately after thoracotomy: 19 (4.4%) 50 ml physiological saline solution | Tumor size (P=0.008) Pathological stage (P < 0.001) Pleural invasion (P < 0.001) |
| Kameyama et al[17] (2014) Retrospective study | Total number of patients: 4, 171 Patients with positive PLC immediately after thoracotomy: 217 (5.2%) Volume unknown | Histology (adenocarcinoma) (P＜0.000, 1) Pathological T category (P＜0.000, 1) Pathological N category (P＜0.000, 1) Pathological M category (P＜0.000, 1) Pathological stage (P＜0.000, 1) Pleural factor (P＜0.000, 1) |
| Nakao et al[12] (2015) Retrospective study | Total number of patients: 1, 572 Patients with positive PLC immediately after thoracotomy: 56 (3.6%) 100 mL physiological saline solution | Pathological T classification (P < 0.001) Pathological N classification (P < 0.001) Pleural invasion (P < 0.001) |
| Tomizawa et al[20] (2016) Retrospective study | Total number of patients: 860 Patients with positive PLC immediately after thoracotomy: 38 (4.4%) 50 mL physiological saline solution | Age (P=0.002) Pleural invasion (P＜0.000, 1) |