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. 2018 Sep 13;8:13746. doi: 10.1038/s41598-018-31700-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Biosynthetic pathway and patterns of accumulation of major flavonoids in different carrot genotypes. Indicated flavonoids were quantified in carrot leaf samples in a 3-year evaluation. Heat maps show fold changes in the accumulation of each flavonoid among the H1, Boléro, I2 and K3 genotypes, presented from left to right. Fold changes are indicated according to the scale bar and were calculated for each compound based on the content in the H1 genotype (auto-scaled values). The biosynthetic pathway was based on the KEGG « Flavone and flavonol biosynthesis » pathway (map00944, Kanehisa et al., 2017).