Table 2.
Healthy vs. PPG | Sensitivity | p-value 1 | p-value 2 | Specificity | p-value 1 | p-value 2 |
---|---|---|---|---|---|---|
Wide-field RNFL thickness map | 92.1 | 0.453 | 89.2 | 1.000 | ||
Wide-field SuperPixel map | 84.2 | 0.453 | 91.9 | 1.000 | ||
SD-OCT | ||||||
RNFL thickness map | 84.2 | 0.453 | 1.000 | 70.3 | 1.000 | 1.000 |
RNFL deviation map | 63.2 | 0.003 | 0.008 | 89.2 | 1.000 | 1.000 |
GC-IPL thickness map | 71.1 | 0.039 | 0.227 | 86.5 | 1.000 | 1.000 |
GC-IPL deviation map | 78.9 | 0.180 | 0.625 | 64.9 | 0.004 | 0.006 |
Thickness map (RNFL+GC-IPL) | 86.8 | 0.687 | 1.000 | 94.6 | 0.625 | 1.000 |
Deviation map (RNFL+GC-IPL) | 71.1 | 0.021 | 0.063 | 100.0 | N/A | N/A |
SD-OCT cpRNFL thickness | ||||||
Clock hours <1% (red) | 47.4 | <0.001 | <0.001 | 94.6 | 0.687 | 1.000 |
Quadrants <1% (red) | 39.5 | <0.001 | <0.001 | 97.3 | 0.375 | 0.625 |
Clock hours <5% (yellow) | 65.8 | 0.006 | 0.016 | 64.9 | 0.012 | 0.002 |
Quadrant <5% (yellow) | 63.2 | 0.003 | 0.021 | 91.9 | 1.000 | 1.000 |
SD-OCT ganglion cell analysis | ||||||
GC-IPL<1% (red) | 60.5 | 0.002 | 0.004 | 86.5 | 1.000 | 0.727 |
GC-IPL<5% (yellow) | 86.8 | 0.727 | 1.000 | 70.3 | 0.092 | 0.057 |
p-value 1 index compared with wide-field RNFL thickness map (McNemar’s test)
p-value 2 index compared with wide-field SuperPixel map (McNemar’s test)
Bold values indicates statistically significant with p-value less than 0.05
PPG preperimetric glaucoma, RNFL retinal nerve fiber layer, cpRNFL circumpapillary RNFL, GC-IPL ganglion cell-inner plexiform layer