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. 2018 May 23;32(9):1483–1492. doi: 10.1038/s41433-018-0104-5

Table 2.

Sensitivities and specificities for discrimination between preperimetric glaucoma and healthy control (categorical variables—criteria)

Healthy vs. PPG Sensitivity p-value 1 p-value 2 Specificity p-value 1 p-value 2
Wide-field RNFL thickness map 92.1 0.453 89.2 1.000
Wide-field SuperPixel map 84.2 0.453 91.9 1.000
SD-OCT
 RNFL thickness map 84.2 0.453 1.000 70.3 1.000 1.000
 RNFL deviation map 63.2 0.003 0.008 89.2 1.000 1.000
 GC-IPL thickness map 71.1 0.039 0.227 86.5 1.000 1.000
 GC-IPL deviation map 78.9 0.180 0.625 64.9 0.004 0.006
 Thickness map (RNFL+GC-IPL) 86.8 0.687 1.000 94.6 0.625 1.000
 Deviation map (RNFL+GC-IPL) 71.1 0.021 0.063 100.0 N/A N/A
SD-OCT cpRNFL thickness
 Clock hours <1% (red) 47.4 <0.001 <0.001 94.6 0.687 1.000
 Quadrants <1% (red) 39.5 <0.001 <0.001 97.3 0.375 0.625
 Clock hours <5% (yellow) 65.8 0.006 0.016 64.9 0.012 0.002
 Quadrant <5% (yellow) 63.2 0.003 0.021 91.9 1.000 1.000
SD-OCT ganglion cell analysis
 GC-IPL<1% (red) 60.5 0.002 0.004 86.5 1.000 0.727
 GC-IPL<5% (yellow) 86.8 0.727 1.000 70.3 0.092 0.057

p-value 1 index compared with wide-field RNFL thickness map (McNemar’s test)

p-value 2 index compared with wide-field SuperPixel map (McNemar’s test)

Bold values indicates statistically significant with p-value less than 0.05

PPG preperimetric glaucoma, RNFL retinal nerve fiber layer, cpRNFL circumpapillary RNFL, GC-IPL ganglion cell-inner plexiform layer