Table 3.
Healthy vs. EG | Sensitivity | p-value 1 | p-value 2 | Specificity | p-value 1 | p-value 2 |
---|---|---|---|---|---|---|
Wide-field RNFL thickness map | 97.2 | 0.453 | 89.2 | 1.000 | ||
Wide-field SuperPixel map | 93.0 | 0.453 | 91.9 | 1.000 | ||
SD-OCT | ||||||
RNFL thickness map | 92.9 | 0.453 | 1.000 | 91.9 | 1.000 | 1.000 |
RNFL deviation map | 88.6 | 0.109 | 0.453 | 89.2 | 1.000 | 1.000 |
GC-IPL thickness map | 80.0 | 0.004 | 0.004 | 86.5 | 1.000 | 0.687 |
GC-IPL deviation map | 88.6 | 0.109 | 0.375 | 64.9 | 0.004 | 0.006 |
Thickness map (RNFL+GC-IPL) | 91.4 | 0.289 | 1.000 | 94.6 | 1.000 | 1.000 |
Deviation map (RNFL+GC-IPL) | 87.1 | 0.065 | 0.219 | 100.0 | N/A | N/A |
cpRNFL thickness | ||||||
Clock hours <1% (red) | 71.4 | <0.001 | <0.001 | 94.6 | 0.687 | 1.000 |
Quadrants <1% (red) | 68.6 | <0.001 | <0.001 | 97.3 | 0.375 | 0.625 |
Clock hours <5% (yellow) | 87.1 | 0.065 | 0.219 | 64.9 | 0.012 | 0.002 |
Quadrant <5% (yellow) | 80.0 | 0.004 | 0.012 | 91.9 | 1.000 | 1.000 |
Macular ganglion cell analysis | ||||||
GC-IPL <1% (red) | 78.6 | 0.002 | 0.006 | 86.5 | 1.000 | 0.727 |
GC-IPL <5% (yellow) | 88.6 | 0.109 | 0.508 | 70.3 | 0.092 | 0.057 |
p-value 1 index compared with wide-field RNFL thickness map (McNemar’s test)
p-value 2 index compared with wide-field SuperPixel map (McNemar’s test)
Bold values indicates statistically significant with p-value less than 0.05
EG early glaucoma, RNFL retinal nerve fiber layer, cpRNFL circumpapillary RNFL, GC-IPL ganglion cell-inner plexiform layer