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. 2018 May 23;32(9):1483–1492. doi: 10.1038/s41433-018-0104-5

Table 3.

Sensitivities and specificities for discrimination between the early glaucoma and healthy control (categorical variables—criteria)

Healthy vs. EG Sensitivity p-value 1 p-value 2 Specificity p-value 1 p-value 2
Wide-field RNFL thickness map 97.2 0.453 89.2 1.000
Wide-field SuperPixel map 93.0 0.453 91.9 1.000
SD-OCT
 RNFL thickness map 92.9 0.453 1.000 91.9 1.000 1.000
 RNFL deviation map 88.6 0.109 0.453 89.2 1.000 1.000
 GC-IPL thickness map 80.0 0.004 0.004 86.5 1.000 0.687
 GC-IPL deviation map 88.6 0.109 0.375 64.9 0.004 0.006
 Thickness map (RNFL+GC-IPL) 91.4 0.289 1.000 94.6 1.000 1.000
 Deviation map (RNFL+GC-IPL) 87.1 0.065 0.219 100.0 N/A N/A
cpRNFL thickness
 Clock hours <1% (red) 71.4 <0.001 <0.001 94.6 0.687 1.000
 Quadrants <1% (red) 68.6 <0.001 <0.001 97.3 0.375 0.625
 Clock hours <5% (yellow) 87.1 0.065 0.219 64.9 0.012 0.002
 Quadrant <5% (yellow) 80.0 0.004 0.012 91.9 1.000 1.000
Macular ganglion cell analysis
 GC-IPL <1% (red) 78.6 0.002 0.006 86.5 1.000 0.727
 GC-IPL <5% (yellow) 88.6 0.109 0.508 70.3 0.092 0.057

p-value 1 index compared with wide-field RNFL thickness map (McNemar’s test)

p-value 2 index compared with wide-field SuperPixel map (McNemar’s test)

Bold values indicates statistically significant with p-value less than 0.05

EG early glaucoma, RNFL retinal nerve fiber layer, cpRNFL circumpapillary RNFL, GC-IPL ganglion cell-inner plexiform layer