Figure 1.
Cartoon representations of the overall structure of hsRuvBL2 monomer and hexamer. (a) The full–length apo hsRuvBL2 monomer. Domains I, II and III are coloured blue, orange/yellow and green, respectively. The visible part of the N-terminal loop and the C-terminal helix are also identified in pink and light green, respectively. A linear schematic representation of the domains of hsRuvBL2, using the same colours, is shown below, highlighting the internal and external portions of domain II. (b) Side and bottom views of the hsRuvBL2 hexamer, highlighting the AAA+ core, using the same colour code.