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. 2018 Sep 7;9:989. doi: 10.3389/fphys.2018.00989

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Copyright © 2018 Bernabeu, Lu, Abu-Qamar, Aiello and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The image series shows the process for hemodynamic analysis. (A) The MA is imaged using AOSLO multiply scattered light imaging modality; (B) a perfusion map of the MA is created (calculated based on pixel-by-pixel standard deviation method) highlighting blood flow; (C) a binary mask of the MA is generated using the outline of the MA and its feeding and draining vessels; (D) a 3-D model of the MA is created under the assumption that it is rotationally symmetric; (E) flow streamlines, colored according to velocity magnitude, are plotted to show the paths followed by blood inside the MA, arrow indicates direction of flow.