Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 23;32(9):1463–1471. doi: 10.1038/s41433-018-0110-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a, b Diabetes-induced apoptosis was inhibited by CNTF. The cell bodies of the dopaminergic amacrine cells were located in the INL. The green staining cells in the INL of CNTF-treated diabetic retinas were more abundant than in vehicle-treated diabetic retinas. One-way ANOVA followed by Fisher’s PLSD multiple comparison tests showed that the staining in the GCL of diabetic retinas was increased (**p < 0.01), but suppressed significantly by CNTF (*p < 0.05). Values are mean ± SD. Scale bar = 50 μm. c CNTF inhibits caspase-3 activity in diabetic rat retinas. Retinal caspase-3 activities in diabetic eyes were significantly higher than those in vehicle-treated non-diabetic eyes. Retinal caspase-3 activities in CNTF-treated diabetic eyes were less than those in vehicle-treated eyes. CNTF application itself only decreased caspase-3 activity in the diabetic rat retina. Data are presented as mean ± SD for each group. One-way ANOVA followed by Fisher’s PLSD multiple comparison tests was used. **p < 0.01 in comparison with the vehicle-treated non-diabetic retinas and ^#p < 0.05 in comparison with the vehicle-treated diabetic retinas