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. 2018 Sep 13;8:13731. doi: 10.1038/s41598-018-31890-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Historical sequence of events (HSE) constructed from super-resolution auto-fluorescence (SRAF) images of the MP2 calcium oxalate (CaOx) kidney stone. (a) The HSE. (b) Sketch depicting individual HSE events. (c) Representative SRAF image composed of merged three pseudo-colored red, green and blue (RGB) channels. Brightness and contrast of the RGB channel intensities are adjusted to highlight the dark crystalline fabrics. Raw images with and without adjustments are presented in Supplementary Fig. 2.