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. 2018 Sep 14;38(5):BSR20180678. doi: 10.1042/BSR20180678

Figure 2. SETDB1 is the common target of the miR-29 family members.

Figure 2

(A) Dual luciferase assay of 293T cells co-transfected with the luciferase constructs containing the SETDB1 3′-UTR_WT or SETDB1 3′-UTR_Mut as well as miR-29s mimics or Scr NC. (B) SETDB1 protein levels was assessed in PC14, A549, and BEAS-2B cells. (C) SETDB1 mRNA levels and (D) SETDB1 protein levels after transfection of miR-29s mimics or Scr NC into A549 and PC14 cells. (E) SETDB1 mRNA levels and (F) SETDB1 protein levels after transfection of miR-29s inhibitors or Scr NC into BEAS-2B cells. *P<0.05; **P<0.01; ***P<0.001