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. 2018 Sep 7;9:1889. doi: 10.3389/fimmu.2018.01889

Table 7.

Characteristics of patients 9 months post-allogeneic hematopoietic stem cell transplantation (HSCT).

Allogeneic-HSCT

Variables sjTREC/μg DNA (median: 166.36)
<median ≥median p

n(%)/n(%)/n(%) n(%)/n(%)/n(%)
Age groups <50/≥50 years old 17 (77.3)/5 (22.7) 26 (89.7)/3 (10.3) 0.268
Sex Male/female 11 (50)/11 (50) 12 (41.4)/17 (58.6) 0.540
Diagnosis ALL/AML/MDS 9 (40.9)/12 (54.5)/1 (4.5) 12 (41.4)/15 (51.7)/2 (6.9) 0.932
Treatment for a prior disease Chemo/chemo plus radio 21 (95.5)/1 (4.5) 28 (96.6)/1 (3.4) 0.999
Bone marrow status before HSCT MRD/activea/CR 7 (31.8)/1 (4.5)/14 (63.6) 6 (20.7)/2 (6.9)/21 (72.4) 0.650
Time between last chemo/radio and HSCT ≥6 months/<6 months 4 (18.2)/18 (81.8) 5 (17.2)/24 (82.8) 0.999
Conditioning regimen MAC/RIC 12 (54.5)/10 (45.5) 23 (79.3)/6 (20.7) 0.059
Stem cell source PBSC/BMSC 10 (45.5)/12 (54.5) 11 (37.9)/18 (62.1) 0.589
Acute-GvHD Absent/present 10 (45.5)/12 (54.5) 12 (41.4)/17 (58.6) 0.771
Chronic-GvHD Absent/present 9 (40.9)/13 (59.1) 15 (51.7)/14 (48.3) 0.443
Bacterial infection episodes Not present/present 7 (31.8)/15 (68.2) 8 (27.6)/21 (72.4) 0.743
CMV infection episodes Not present/present 1 (4.5)/21 (95.5) 9 (31)/20 (69) 0.030
Fungal infection episodes Not present/present 21 (99.5)/1 (4.5) 25 (86.2)/4 (13.8) 0.375
Clinical status Dead/alive 4 (18.2)/18 (81.8) 2 (6.9)/27 (93.1) 0.383
Total 51 (100%) 22 (100) 29 (100) Not applied

ALL, acute lymphocytic leukemia; AML, acute myeloid leukemia; chemo, chemotherapy; BMSC, bone marrow stem cell; CMV, cytomegalovirus; CR, complete response; GvHD, graft-versus-host disease; HD, Hodgkin’s disease; HSCT, hematological stem cell transplantation; MAC, myeloablative conditioning; MDS, myelodysplastic syndrome; MRD, minimal residual disease; MM, multiple myeloma; PBSC, peripheral blood stem cell; PR, partial response; radio, radiotherapy; RIC, reduced intensity conditioning; sjTREC, signal joint TREC.

aActive: three cases of MDS have not received any treatment before HSCT.