FIGURE 1.

Summarized GO annotation results shared by AD and IS. The complete GO annotation results shared by AD and IS are summarized and reorganized here, with only more fine-grained terms labeled and classified into different functional categories: transcriptional and post-transcriptional regulation, synapse, endocytic membrane traffic, signaling transduction, immune process, multi-organism process, protein catabolic metabolism, cell adhesion, and others, which are shown in nodes. The relevant GO terms of biological process, cellular component, and molecular function are shown in targets. The threshold for statistical significance for a GO term is P < 0.05 in both AD and IS. The edges connecting the nodes and targets are attributed by the value of –log₁₀ P.