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. 2018 Sep 7;12:609. doi: 10.3389/fnins.2018.00609

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Copyright © 2018 Perea, Lleó, Alcolea, Fortea, Ávila and Bolós.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CX3CL1 decreases in the CSF of AD patients. N = 14 samples per group: control (C), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) were analyzed by ELISA of CX3CL1. Samples were run in duplicate. The concentration of CX3CL1 was analyzed in CSF (A) and plasma samples (B). CX3CL1 decreased in the CSF of AD compared to control and MCI (A). However, no difference was observed in the concentration of CX3CL1 in plasma samples (B). Bars show means ± SE. ^∗∗p ≤ 0.01, ^∗∗∗p ≤ 0.001.