Table 1.
Demographics and CSF biomarker levels of the participant.
| Group | Cases (N) | Age (Mean years ± SD) | Gender (female/male) | MMSE ± SD | CSF ABETA42 (pg/ml) ± SD | CSF P-TAU (pg/ml) ± SD | CSF TAU (pg/ml) ± SD | CX3CL1 (ng/ml) ± SD |
|---|---|---|---|---|---|---|---|---|
| Control | 14 | 64 ± 2.92 | 7/8 | 29 ± 0.88 | 802 ± 218 | 59 ± 42 | 244 ± 46 | 0.31 ± 0.05 |
| MCI | 14 | 70 ± 3.52∗∗∗ | 9/5 | 26 ± 2.95∗∗ | 438 ± 58∗∗∗ | 112 ± 51∗ | 761 ± 374 n.s | 0.28 ± 0.07 |
| AD | 14 | 68 ± 4.18∗ | 9/5 | 21.5 ± 3.5 | 453 ± 101∗∗∗ | 109 ± 46∗ | 762 ± 377 n.s | 0.166 ± 0.05∗∗∗ |
Three groups of samples: C, control; MCI, mild cognitive impairment; AD, Alzheimer’s disease, with 14 cases (N) in each group, were analyzed. The average age, gender, memory test (MMSE), amount of CSF Aβ42, CSF ptau, CSF tau and CSF CX3CL1 are detailed in the table. Results are expressed as average concentration ± standard deviation (SD). Statistics of the measures are related to control: ∗p ≤ 0.05, ∗∗p ≤ 0.01, and ∗∗∗p ≤ 0.001.