Table 3.
Number and percentage of study arms including each component and estimates of corresponding incremental odds ratios (iOR) parameter, with 95% Credible Intervals (CrI), for remission, response and dropouts
| Remission | Response | Dropouts | ||||
|---|---|---|---|---|---|---|
| Component | n (%) of included arms | iOR (95% CrI) | n (%) of included arms | iOR (95% CrI) | n (%) of included arms | iOR (95% CrI) |
| Third-wave components (3w) | 1 (0.8%) | 1.97 (0.34–14.44) | 0 (0.0%) | 1 (0.75%) | 0.55 (0.08–3.63) | |
| Interoceptive exposure (ine) | 54 (40.3%) | 1.49 (0.94– 2.36) | 48 (38.7%) | 1.43 (0.94–2.16) | 58 (37.9%) | 0.95 (0.53–1.70) |
| Face-to-face setting (ftf) | 82 (61.2%) | 1.27 (0.57– 2.66) | 78 (62.9%) | 1.79 (0.93–3.53) | 97 (63.4%) | 0.54 (0.17–1.51) |
| Cognitive restructuring (cr) | 69 (51.2%) | 1.11 (0.73– 1.73) | 61 (49.2%) | 0.87 (0.60–1.27) | 74 (48.4%) | 1.00 (0.60–1.70) |
| Placebo effect (pl) | 101 (75.4%) | 0.97 (0.35–2.48) | 94 (75.8%) | 1.04 (0.29–3.35) | 116 (75.8%) | 15.18 (1.67–347.23) |
| Breathing retraining (br) | 45 (33.6%) | 0.84 (0.54– 1.26) | 40 (32.3%) | 1.16 (0.81–1.67) | 51 (33.3%) | 0.71 (0.45–1.14) |
| Psychoeducation (pe) | 89 (66.4%) | 0.84 (0.45– 1.52) | 84 (67.7%) | 1.17 (0.68–2.03) | 100 (65.4%) | 0.93 (0.43–2.03) |
| Psychological support (ps) | 90 (67.2%) | 0.79 (0.34– 1.90) | 84 (67.7%) | 0.86 (0.40–1.84) | 105 (68.6%) | 1.38 (0.44–4.66) |
| In vivo exposure (ive) | 64 (47.8%) | 0.78 (0.50– 1.22) | 61 (49.2%) | 0.96 (0.66–1.46) | 71 (46.4%) | 0.86 (0.49–1.48) |
| Virtual-reality exposure (vre) | 7 (5.22%) | 0.71 (0.25– 1.99) | 8 (6.5%) | 0.41 (0.19–0.84) | 6 (3.9%) | 1.77 (0.58–5.37) |
| Muscle relaxation (mr) | 30 (22.4%) | 0.59 (0.40– 0.90) | 29 (23.4%) | 0.64 (0.46–0.88) | 35 (22.9%) | 1.07 (0.64–1.77) |
| Waiting component (w) | 34 (25.4%) | 0.38 (0.12– 1.23) | 30 (24.9%) | 0.80 (0.21– 2.86) | 38 (24.8%) | 5.26 (0.59–121.51) |
| τ | 0.40 (0.05– 0.73) | 0.23 (0.02–0.55) | 0.53 (0.11–0.91) | |||
| Coefficient of the variance in the meta-regression | −1.96 (−2.72 to −1.30) | −1.66 (−2.26 to −1.08) | − | |||
Larger values of the parameters indicate respectively, larger remission, response and dropout rates. Components are ordered according to iORs for remission, from the most to the least beneficial.
The lower part of the table reports the median heterogeneity standard deviation (τ) for the three outcomes and the regression coefficient for the two outcomes for which analyses were adjusted for small study effects.