Figure 2.

Alkyl-Heck-Type Reaction of Secondary and Tertiary Aliphatic Acids

Top: One-pot process from aliphatic acid: First, acid (1.5 mmol), TBHP (1.5 mmol), and TFAA (2.0 mmol) at 0°C–rt for 3–5 hr, and then THF (2 mL), styrene 27 (0.5 mmol), and HOTf (0.05 mmol) were added. The mixture was stirred at 50°C for 8 hr; yields of isolated products.

Bottom: Styrene 27 (0.5 mmol), perester (1.25 mmol), and HOTf (0.1 mmol) at 80°C for 8 hr for 35, 36, 38, 42, and 43.

See also Figures S95–S127.