Figure 3. Selected Gray Matter (GM) and White Matter (WM) Measures Associated With Brain Changes After Prenatal Exposure to Selective Serotonin Reuptake Inhibitors (SSRIs).

Receiver operating characteristics analysis curve showing cross-validated diagnostic accuracy of a linear regression model predicting SSRI exposure (leave-1-out cross validation). We tested 3 logistic regression models with different sets of the selected brain measures as predictors: GM+WM (orange), WM (gray), and GM (blue) models (predictors: for GM, right amygdala volume and right insula volume; for WM, amygdala-insula connectivity). Shaded areas are confidence bounds (estimated in 5000 bootstrap samples).