Table 2. Group Comparison of Gray Matter Volumes (Voxel-Based Morphometry).

Brain Region	Coordinates x, y, z, mm	Whole-Brain Corrected P Valuea	Cluster Size, mm3
Contrast: SSRI>PMD + HC
Right amygdala	17, −1, −11	= .01	397
Right insula/orbitofrontal cortex	28, 8, −5	.01	50
Right superior frontal gyrus	3, 7, 36	.03	129
Left occipital gyrus	−20, −63, 9	.04	116
Contrast: SSRI>PMD
Right amygdala	16, −2, −12	.03	65
Right insula/orbitofrontal cortex	29, 9, −6	.03	70
Right superior frontal gyrus	3, 10, 35	.03	35
	0, 14, 29	.03	19
Right precuneus	29, 9, −6	.03	70
Contrast: SSRI>HC
Right amygdala/insula	15, −2, 08	.02	211
Right caudate	7, 0, −2	.02	26
Contrast: SSRI>PMD + HC
Right amygdala	17, −1, −11	.01	397
Right insula/orbitofrontal cortex	28, 8, −5	.01	50
Right superior frontal gyrus	3, 7, 36	.03	129
Left occipital gyrus	−20, −63, 9	.04	116

Abbreviations: HC, healthy control; PMD, prenatal maternal depression; SSRI, selective serotonin reuptake inhibitor.

^aSignificance was determined using randomization permutation.