Table 3.
Outcomes.
| Outcomes of 360 Express procedure | |
| Patients (n) | 30 |
| Median percentage of Barrett's surface regression at three monthsa, % (IQR) | 90 (77–95) |
| Median total procedure time, min (IQR) | 31 (28–38) |
| Median ablation time, min (IQR) | 20 (17–25) |
| Adverse events of self-sizing session, n (%) | 4 (13) |
| Mild adverse events | 3 |
| - acute laceration | |
| - early atrial fibrillation | |
| - late dysregulation of diabetes mellitus | |
| Moderate complication | 1 |
| - early dysphagia, no endoscopic esophageal abnormalities | |
| Outcomes of entire treatment phase | |
| Patients (n) | 30 |
| Stenosis at any point during treatment phase requiring intervention, n (%) | 3 (10) |
| Complete eradication of dysplasia at end of the treatment phase, n (%) | |
| - Intention to treat analysis | 29/30 (97) |
| - Per protocol analysis | 28/28 (100) |
| Complete eradication of intestinal metaplasia at end of the treatment phase | |
| - Intention to treat analysis | 26/30 (87) |
| - Per protocol analysis | 26/28 (93) |
| Median total number of treatment sessionsb per patient, (IQR) | 3 (IQR 2–4) |
| Number of circumferential RFA sessions per patient, n | 1 |
| Median number of focal RFA sessions per patient, (IQR) | 1 (1–2) |
| Number of patients who underwent APCc, n | 13 |
| - One session | 8 |
| - Two sessions | 5 |
| Number of patients who underwent EMR, n | |
| - Escape treatment for residual IM after RFA (n = 1) | 2 |
| - Diagnosis of elevated BE islands (n = 1)d | |
a
Mean of two independent scores by expert endoscopists.
b
Treatment sessions included circumferential RFA, focal RFA, APC and EMR.
c
APC was used to treat small areas of Barrett's mucosa (islands/tongues < 10 mm).
d
Histology showed non-dysplastic IM.
APC: argon plasma coagulation; BE: Barrett's esophagus; EMR: endoscopic mucosal resection; IM: intestinal metaplasia; IQR: interquartile range; min: minutes; n: number of patients; RFA: radiofrequency ablation.