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. 2015 Dec;12(12):S222–S227. doi: 10.1513/AnnalsATS.201508-484PL

Table 1.

2014 Pittsburgh-Munich International Lung Conference: Aging and Lung Disease

Program Agenda
Opening lecture: Research in Aging: Relevance, Challenges, and Impact, Kevin P. High, M.D., M.S.
Session 1: Mitochondria and Aging
 Mitochondrial Metabolism, Sirtuins, and Aging, Michael N. Sack, M.D., Ph.D.
 Inside, Outside, Upside Down: DAMPs and Redox Regulate Immunity, Michael Lotze, M.D.
 Cardiolipin and Mitochondrial Apoptosis, Valerian E. Kagan, Ph.D., D.Sc.
 Age-related PINK1 Deficiency Impairs Mitochondrial Homeostasis and Promotes Lung Fibrosis, Marta Bueno Fernandez, Ph.D.
Session 2: Age, Genetics, and Lung Diseases
 Genetics of Familial IPF, Timothy Blackwell, M.D.
 Telomeres and Telomerase in Lung Diseases, Mary Armanios, M.D.
 Is IPF a Stem Cell Disease? Piero Anversa, M.D.
 The Aging ECM in Chronic Lung Diseases, Oliver Eickelberg, M.D.
 Twist in the IPF Fibroblast, Daniel Kass, M.D.
Session 3: Molecular Drivers of Cell Aging, and Their Impact in the Respiratory System
 Update on Clinical Trials in IPF, Kevin Gibson, M.D.
 Aging and Wnt Pathway, Melanie Königshoff, M.D., Ph.D.
 Malfolded Proteins, Proteostasis, Lung Disease, and Aging, William E. Balch, Ph.D.
 Immunosenescence and Aging, Patty Lee, M.D.
 Studying Lung Aging in Murine Models, Enid R. Neptune, M.D.
Session 4: The “OMICS” of Aging
 Genetics and Genomics of Human Aging, Stuart K. Kim, Ph.D.
 Metabolomics of Aging, Dean Jones, Ph.D.
 Proteomics: State-of-the-Art to Assess Aging, Matthias Mann, Ph.D.
Session 5: Lung Diseases and Aging
 COPD, an Early Aging Disease?, Frank C. Sciurba, M.D., F.C.C.P.
 IPF and Aging, Moisés Selman, M.D.
 Age and Susceptibility to ARDS, Gustavo Matute-Bello, M.D.
 Cellular Senescence in the Aging Lung: Implications for Epigenetic Changes and Cancer, John Michael Sedivy, Ph.D.
 Smoke Responses in Aging Mice, Ali Önder Yildirim, D.V.M.
Session 6: Aging Lung Cells and Repair
 Fibroblast Activation Protein (FAP) Is an Endogenous Regulator of Pulmonary Fibrosis, Ming-Hui Fan, M.D.
 Impact of Aging on Mesenchymal Stem Cells, Mechanisms and Therapeutic Implications, Mauricio Rojas, M.D.
 Lung Endothelial Cells Adaptation to Apoptotic Stress, Irina Petrache, M.D.
 Hyaluronan Interactions with TLR4 Regulate Type 2 Alveolar Cell Renewal and the Severity of Pulmonary Fibrosis, Paul Noble, M.D.
Keynote speaker: Aging and Chronic Disease – A View from the Aging Side, Brian K. Kennedy, Ph.D.