Table 1.
Characteristics of Multi-Ethnic Study of Atherosclerosis Lung Study participants without prevalent clinical chronic lower respiratory disease, by quartile of Pi10
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |
|---|---|---|---|---|
| n* | 1,508 | 1,508 | 1,509 | 1,508 |
| Age, yr, mean (SD) | 62.2 (9.8) | 62.0 (10.3) | 62.1 (10.3) | 62.6 (10.3) |
| Male sex, n (%) | 660 (43.8) | 655 (43.4) | 752 (49.8) | 840 (55.7) |
| Race/ethnicity, n (%) | ||||
| White | 707 (46.9) | 565 (37.5) | 536 (35.5) | 498 (33.0) |
| African American | 537 (35.6) | 379 (25.1) | 394 (26.1) | 340 (22.6) |
| Hispanic/Latino American | 159 (10.5) | 365 (24.2) | 358 (23.7) | 454 (30.1) |
| Asian American | 105 (7.0) | 199 (13.2) | 221 (14.7) | 216 (14.3) |
| BMI, kg/m2, mean (SD) | 27.7 (5.3) | 27.5 (5.2) | 28.2 (5.3) | 29.2 (5.3) |
| Smoking status, n (%) | ||||
| Never | 682 (45.2) | 705 (46.8) | 717 (47.6) | 664 (44.1) |
| Former | 628 (41.6) | 620 (41.2) | 569 (37.7) | 601 (39.9) |
| Current | 198 (13.1) | 181 (12.0) | 222 (14.7) | 242 (16.1) |
| Pack-years, median (IQR)† | 15.0 (3.5–31.0) | 12.0 (2.0–30.0) | 12.8 (3.2–29.1) | 17.2 (4.0–35.2) |
| CT measures | ||||
| Pi10, mm, median (IQR) | 4.32 (4.20–4.40) | 4.55 (4.51–4.59) | 4.70 (4.66. 4.75) | 4.92 (4.85–5.06) |
| Wall thickness, mm, median (IQR) | 1.33 (1.24–1.42) | 1.44 (1.34–1.50) | 1.49 (1.40–1.57) | 1.56 (1.45–1.67) |
| Lumen diameter, mm, median (IQR) | 3.39 (2.55–4.32) | 3.28 (2.54–4.17) | 3.15 (2.48–4.06) | 3.03 (2.42–4.00) |
| Percent emphysema, median (IQR) | 2.70 (1.13–5.70) | 3.19 (1.60–5.77) | 3.04 (1.36–5.45) | 2.17 (0.79–4.92) |
| CT scanner type, n (%)‡ | ||||
| EBT/Imatron | 510 (33.8) | 861 (57.1) | 856 (56.7) | 939 (62.3) |
| MDCT/Siemens | 183 (12.1) | 547 (36.3) | 626 (41.5) | 550 (36.5) |
| MDCT/GE | 815 (54.1) | 100 (6.6) | 27 (1.8) | 19 (1.3) |
Definition of abbreviations: BMI = body mass index; CT = computed tomography; EBT = electron beam computed tomography scanner; IQR = interquartile range; MDCT = multidetector computed tomography scanner; Pi10 = average wall thickness for a hypothetical airway of 10-mm lumen perimeter on computed tomography; SD = standard deviation.
Numbers reported as mean (SD) or number (percent) unless otherwise noted.
Excludes all participants with prevalent chronic lower respiratory disease, defined as self-reported asthma or emphysema and/or inhaler use at study baseline.
Among ever smokers.
Imatron EBT was used at three sites (Columbia, Northwestern University, and University of California, Los Angeles). Siemens MDCT was used at two sites (Johns Hopkins and University of Minnesota). GE Healthcare Life Sciences MDCT was used at one site (Wake Forest University).